Lub luag haujlwm ntawm cov neeg sawv cev chelating hauv cov khoom ntxuav
Chelate, chelate uas tsim los ntawm cov neeg sawv cev chelating, los ntawm lo lus Greek Chele, txhais tau tias tus cw ntses. Chelates zoo li tus cw ntses tuav cov hlau ions, uas ruaj khov heev thiab yooj yim tshem tawm lossis siv cov hlau ions no. Xyoo 1930, thawj chelate tau tsim nyob rau hauv lub teb chaws Yelemees - EDTA (ethylenediamine tetraacetic acid) chelate rau kev kho mob ntawm cov neeg mob hnyav lom, thiab tom qab ntawd chelate tau tsim thiab siv rau kev ntxuav tshuaj txhua hnub, zaub mov, kev lag luam thiab lwm yam kev siv.
Tam sim no, cov chaw tsim khoom tseem ceeb ntawm cov neeg sawv cev chelating hauv ntiaj teb suav nrog BASF, Norion, Dow, Dongxiao Biological, Shijiazhuang Jack thiab lwm yam.
Thaj av Asia-Pacific yog lub khw loj tshaj plaws rau cov neeg sawv cev chelating, nrog ntau dua 50% feem thiab kwv yees li ntawm US $ 1 billion, nrog rau cov ntawv thov tseem ceeb hauv kev lag luam ntxuav khaub ncaws, kev kho dej, kev saib xyuas tus kheej, ntawv, khoom noj thiab dej haus.
(Cov qauv molecular ntawm tus neeg sawv cev chelating EDTA)
Cov neeg sawv cev chelating tswj cov hlau ions los ntawm chelating lawv cov multi-ligands nrog cov hlau ion complexes los tsim cov chelates.
Los ntawm cov txheej txheem no, nws tuaj yeem nkag siab tias ntau cov molecules nrog ntau-ligands muaj peev xwm chelation zoo li no.
Ib qho ntawm cov EDTA uas feem ntau siv yog saum toj no, uas tuaj yeem muab 2 lub nitrogen atoms thiab 4 lub carboxyl oxygen atoms los koom tes nrog cov hlau, thiab tuaj yeem siv 1 molecule los qhwv cov calcium ion uas xav tau 6 qhov kev sib koom tes, tsim cov khoom ruaj khov heev nrog lub peev xwm chelation zoo heev. Lwm cov chelators siv feem ntau suav nrog sodium phytate xws li sodium gluconate, sodium glutamate diacetate tetrasodium (GLDA), sodium amino acids xws li methylglycine diacetate trisodium (MGDA), thiab polyphosphates thiab polyamines.
Raws li peb txhua tus paub, txawm tias nyob hauv dej kais lossis hauv cov dej ntuj, muaj calcium, magnesium, hlau plasma, cov hlau ions no hauv kev nplua nuj mus sij hawm ntev, yuav coj cov teebmeem hauv qab no rau peb lub neej txhua hnub:
1. Cov ntaub tsis tau ntxuav kom huv, ua rau cov nplai av tawm, tawv thiab tsaus ntuj.
2. Tsis muaj tshuaj ntxuav uas tsim nyog rau ntawm qhov chaw tawv, thiab muaj cov nplai av
3. Cov nplai tso rau hauv cov tais diav thiab khob iav
Qhov nyuaj ntawm dej yog hais txog cov calcium thiab magnesium ions uas muaj nyob hauv dej, thiab dej tawv yuav txo qhov cuam tshuam ntawm kev ntxuav. Hauv cov khoom siv ntxuav khaub ncaws, tus neeg sawv cev chelating tuaj yeem ua rau muaj calcium, magnesium thiab lwm yam hlau ions hauv dej, yog li ua kom cov dej mos, tiv thaiv calcium thiab magnesium plasma los ntawm kev ua rau muaj tus neeg sawv cev nquag hauv cov tshuaj ntxuav khaub ncaws, thiab tsis txhob cuam tshuam rau qhov cuam tshuam ntawm kev ntxuav, yog li txhim kho qhov ua tau zoo ntawm cov khoom ntxuav khaub ncaws.
Tsis tas li ntawd xwb, cov neeg sawv cev chelating kuj tseem tuaj yeem ua rau cov tshuaj ntxuav kom ruaj khov dua thiab tsis yooj yim rau kev lwj thaum raug cua sov lossis khaws cia ntev.
Qhov ntxiv ntawm tus neeg sawv cev chelating rau hauv cov tshuaj ntxhua khaub ncaws tuaj yeem txhim kho nws lub zog ntxuav, tshwj xeeb tshaj yog nyob rau hauv thaj chaw uas cov nyhuv ntxuav raug cuam tshuam los ntawm qhov nyuaj, xws li sab qaum teb, sab qab teb hnub poob thiab lwm qhov chaw uas muaj dej tawv siab, tus neeg sawv cev chelating kuj tseem tuaj yeem tiv thaiv cov dej thiab cov xim tsis txhob lo rau ntawm qhov chaw ntawm cov ntaub, yog li cov tshuaj ntxhua khaub ncaws nkag tau yooj yim dua thiab yooj yim lo rau ntawm qhov chaw ntawm cov khaub ncaws, txhim kho cov nyhuv ntxuav tib lub sijhawm. Txhim kho qhov dawb thiab mos, kev ua tau zoo tsis yog xim grey thiab qhuav tawv.
Tsis tas li ntawd hauv kev ntxuav qhov chaw tawv thiab kev ntxuav cov tais diav, tus neeg sawv cev chelating hauv cov tshuaj ntxuav tes tuaj yeem txhim kho qhov kev yaj thiab kev sib kis ntawm cov tshuaj ntxuav tes, yog li cov xim thiab nplai yooj yim tshem tawm, thiab qhov kev ua tau zoo yog tias cov nplai tsis tuaj yeem nyob, qhov chaw yog pob tshab dua, thiab lub iav tsis dai dej zaj duab xis. Cov neeg sawv cev chelating kuj tuaj yeem sib xyaw nrog cov pa oxygen hauv huab cua los tsim cov khoom ruaj khov uas tiv thaiv kev oxidation ntawm cov hlau nto.
Tsis tas li ntawd xwb, cov nyhuv chelating ntawm cov neeg sawv cev chelating rau cov hlau ions kuj tseem siv rau hauv cov tshuaj ntxuav yeeb nkab rau kev tshem tawm xeb.